I’m using the latest Adobe Cloud 21.2.0 Photoshop release at the time I’m writing this article. In this article are the step-by-step instructions on how to separate your artwork from a CMYK or RGB Photoshop file into spot colors. Especially the old school way that was taught to me. Let’s face it, getting others to do it is its own offshoot industry.īut, it’s fairly easy to learn. Plenty of folks or art departments in this industry struggle with separating simulated process spot color seps for Photoshop.